Chris A. Brosey

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

Jerry H. Houl, Zu Ye, Chris A. Brosey et al. · Nature Communications · 2019 · 132 citations · Full text

Medicine, Cancer Biology, Oncology +16

A new structural framework for integrating replication protein A into DNA processing machinery

Chris A. Brosey, Chunli Yan, Susan E. Tsutakawa et al. · Nucleic Acids Research · 2013 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Checkpoint Kinase ATR Promotes Nucleotide Excision Repair of UV-induced DNA Damage via Physical Interaction with Xeroderma Pigmentosum Group A

Steven M. Shell, Zhengke Li, Nikolozi Shkriabai et al. · Journal of Biological Chemistry · 2009 · 86 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A Quantitative Assay Reveals Ligand Specificity of the DNA Scaffold Repair Protein XRCC1 and Efficient Disassembly of Complexes of XRCC1 and the Poly(ADP-ribose) Polymerase 1 by Poly(ADP-ribose) Glycohydrolase

In Kwon Kim, Roderick A. Stegeman, Chris A. Brosey et al. · Journal of Biological Chemistry · 2014 · 59 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor

Chris A. Brosey, Chris Ho, Winnie Long et al. · Structure · 2016 · 58 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12