Nature Neuroscience · 2016 · 108 citations · 53 references
Life SciencesMolecular BiologyNeuroscienceChromatin BiologyEpigeneticsTranscriptional RegulationChromatinHistone ModificationsHistone ProteinsFoxo Transcriptional RegulationHistone DeacetylasesHistone DeacetylationMecp2 FunctionSocial Behavior Development
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Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
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