Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex - Concepedia

Concepedia

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson, Carol D. Laherty, Bryan M. Turner, Robert N. Eisenman, Adrian Bird

Nature · 1998 · 3.4K citations · 27 references

Concepts

Histone ModificationsChromatinTranscriptional RegulationChromatin RemodelingNatural SciencesEpigenetic ChangeGene RegulationMolecular BiologyHistone Deacetylase ComplexGene ExpressionMedicineCell BiologyEpigeneticsTranscriptional RepressionTranscription RegulationMethyl-cpg-binding Protein Mecp2

References

27

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983

EngineeringRna Polymerase IiIsolated Mammalian Nuclei+19

11.6K citations

Role for DNA methylation in genomic imprinting

Rudolf Jaenisch · Nature · 1993

ChromatinEpigenetic ChangeGenetics+5

1.9K citations

Role for DNA methylation in genomic imprinting

E. Li, Caroline Beard, Rudolf Jaenisch · Trends in Genetics · 1994

ChromatinEpigenetic ChangeGenetics+5

1.7K citations

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA

Joe Lewis, Richard R. Meehan, William J. Henzel et al. · Cell · 1992

ChromatinChromatin RemodelingEpigenetic Change+12

1.4K citations

MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin

Xinsheng Nan, Francisco J. Campoy, Adrian Bird · Cell · 1997

Genomic MechanismMolecular BiologyEpigenetics+16

1.3K citations