Chromatin Architecture
Chromatin Architecture is the three-dimensional structural organization of chromatin within the nucleus that governs spatial genome organization and regulates genomic functions through specific patterns of compaction, looping, and topological domain formation.
9.9K
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1M
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35.4K
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4K
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2017–2026
2.9K
Variants
3D Genome Organization
Parents
Children
A/b Chromatin CompartmentsCentromeric Chromatin OrganizationChromatin Conformation Capture AnalysisEpigenetic Chromatin StatesInterphase Chromatin OrganizationLoop Extrusion MechanismPolycomb-mediated Chromatin ArchitectureTelomeric Chromatin StructureTranscription-dependent Chromatin Remodeling
9.9K
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Suhas S.P. Rao, Miriam Huntley, Neva C. Durand et al. · Cell · 2014 · 9.9K citations · Full text
Topological domains in mammalian genomes identified by analysis of chromatin interactions
Jesse R. Dixon, Siddarth Selvaraj, Feng Yue et al. · Nature · 2012 · 7.4K citations · Full text
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie et al. · Cell · 2006 · 5.4K citations · Full text
Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
John L. Rinn, Michael A. Kertesz, Jordon K. Wang et al. · Cell · 2007 · 4.3K citations · Full text
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University of Massachusetts Chan Medical School, United States
59 publications · 27K citations
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Howard Hughes Medical Institute
Chevy Chase, United States
168 h-index
1.3K publications
291.3K citations
Harvard University
Cambridge, United States
149 h-index
1.5K publications
411.5K citations
National Institutes of Health
Bethesda, United States
121 h-index
1.2K publications
174.6K citations

Centre National de la Recherche Scientifique
Paris, France
112 h-index
2.1K publications
219.6K citations
National Cancer Institute
Bethesda, United States
98 h-index
735 publications
115.5K citations
Stanford University
Stanford, United States
94 h-index
736 publications
198.8K citations
Massachusetts Institute of Technology
Cambridge, United States
91 h-index
458 publications
164.8K citations
University of Massachusetts Chan Medical School
Worcester, United States
89 h-index
653 publications
132.2K citations
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259 publications · 109.7K citations
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238 publications · 102K citations
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313 publications · 58K citations
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PNAS · 429 publications · 57.1K citations
130
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241 publications · 34.5K citations
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