Concepedia

Methyl-cpg Binding Proteins

Methyl-CpG Binding Proteins is a class of epigenetic reader proteins that selectively recognize and bind to methylated CpG dinucleotides in DNA, thereby mediating the recruitment of chromatin-modifying complexes to regulate neuronal gene expression.

1K

Publications

100.2K

Citations

5.6K

Authors

1.4K

Institutions

Publications per year

2017–2026

245

Variants

MbpsMethyl-cpg-binding Proteins

Parents

Publications

1K

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Ruthie E. Amir, Ignatia B. Van den Veyver, Mimi Wan et al. · Nature Genetics · 1999 · 5K citations

, , +9

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

, , +16

DNA Methylation-Related Chromatin Remodeling in Activity-Dependent <i>Bdnf</i> Gene Regulation

Keri Martinowich, Daisuke Hattori, Hao Wu et al. · Science · 2003 · 1.4K citations

, , +14

Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

Brian Hendrich, Adrian Bird · Molecular and Cellular Biology · 1998 · 1.4K citations · Full text

, , +12

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma et al. · Science · 2017 · 1.3K citations · Full text

, , +12

1–5 of 1K

Authors

5.6K

  1. AB
    Adrian Bird

    University of Edinburgh, United Kingdom

    39 publications · 14.1K citations

    34

    h-index

  2. ME
    Manel Esteller

    Institut d'Investigació Biomédica de Bellvitge, Spain

    16 publications · 969 citations

    14

    h-index

  3. JL
    Jeffrey L. Neul

    Baylor College of Medicine, United States

    13 publications · 1.6K citations

    13

    h-index

  4. HY
    Huda Y. Zoghbi

    Baylor College of Medicine, United States

    13 publications · 7.6K citations

    13

    h-index

  5. JH
    Joussef Hayek

    Azienda Ospedaliera Universitaria Senese, Italy

    12 publications · 584 citations

    12

    h-index

1–5 of 5.6K

Institutions

1.4K

  1. University of Edinburgh

    Edinburgh, United Kingdom

    34 h-index

    154 publications

    37.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    27 h-index

    135 publications

    7.7K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    73 publications

    23.5K citations

  4. Baylor College of Medicine

    Houston, United States

    26 h-index

    120 publications

    35.9K citations

  5. Wellcome Centre for Cell Biology

    Edinburgh, United Kingdom

    25 h-index

    99 publications

    19K citations

  6. Inserm

    Paris, France

    23 h-index

    110 publications

    6.3K citations

  7. University of Toronto

    Toronto, Canada

    22 h-index

    102 publications

    7.2K citations

  8. Johns Hopkins University

    Baltimore, United States

    22 h-index

    99 publications

    9.6K citations

1–8 of 1.4K

Venues

  1. Journal of Biological Chemistry

    JBC · 46 publications · 5.7K citations

    37

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 6K citations

    36

    h-index

  3. Nucleic Acids Research

    57 publications · 7.1K citations

    36

    h-index

  4. Molecular and Cellular Biology

    MCB · 38 publications · 6K citations

    34

    h-index

  5. PLoS ONE

    38 publications · 3K citations

    28

    h-index

1–5