Concepedia

Epigenetic Gene Repression

Epigenetic Gene Repression is a molecular regulatory mechanism involving heritable alterations in gene expression that occur without changes to the DNA sequence, distinguished by the stable silencing of genes through chemical modifications such as DNA methylation and histone deacetylation.

835

Publications

78.5K

Citations

5.6K

Authors

1.3K

Institutions

Publications per year

2017–2026

246

Parents

Publications

835

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

, , +16

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Peter Lloyd Jones, Gert Jan C. Veenstra, Paul A. Wade et al. · Nature Genetics · 1998 · 2.7K citations

, , +10

Histone H3 Methylation by Set2 Directs Deacetylation of Coding Regions by Rpd3S to Suppress Spurious Intragenic Transcription

Michael J. Carrozza, Bing Li, Laurence Florens et al. · Cell · 2005 · 1.3K citations

, , +17

RNAi-Mediated Targeting of Heterochromatin by the RITS Complex

André Verdel, Songtao Jia, Scott A. Gerber et al. · Science · 2004 · 1.2K citations · Full text

, , +17

The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation

François Fuks, Paul J. Hurd, Daniel Wolf et al. · Journal of Biological Chemistry · 2003 · 986 citations · Full text

, , +15

1–5 of 835

Authors

5.6K

  1. ME
    Manel Esteller

    Institut d'Investigació Biomédica de Bellvitge, Spain

    8 publications · 603 citations

    8

    h-index

  2. SM
    Silvère M. van der Maarel

    Leiden University Medical Center, Netherlands

    8 publications · 1.2K citations

    8

    h-index

  3. SJ
    Stephen J. Tapscott

    Fred Hutch Cancer Center, United States

    8 publications · 1.2K citations

    8

    h-index

  4. RT
    Rabi Tawil

    University of Rochester Medical Center, United States

    8 publications · 1.2K citations

    8

    h-index

  5. DZ
    Dao‐Xiu Zhou

    Institut des Sciences des Plantes de Paris Saclay, France

    7 publications · 303 citations

    7

    h-index

1–5 of 5.6K

Institutions

1.3K

  1. Harvard University

    Cambridge, United States

    26 h-index

    130 publications

    30.6K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    26 h-index

    50 publications

    10.6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    89 publications

    6.6K citations

  4. Chinese Academy of Sciences

    Beijing, China

    19 h-index

    115 publications

    7.7K citations

  5. Inserm

    Paris, France

    19 h-index

    74 publications

    4.1K citations

  6. University of Southern California

    Los Angeles, United States

    17 h-index

    76 publications

    6.3K citations

  7. National Institutes of Health

    Bethesda, United States

    16 h-index

    71 publications

    26.2K citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    16 h-index

    80 publications

    8.5K citations

1–8 of 1.3K

Venues

  1. Molecular and Cellular Biology

    MCB · 49 publications · 5.9K citations

    39

    h-index

  2. Journal of Biological Chemistry

    JBC · 40 publications · 4.1K citations

    32

    h-index

  3. Nucleic Acids Research

    40 publications · 3.5K citations

    31

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 38 publications · 4.7K citations

    31

    h-index

  5. Nature Communications

    30 publications · 3.4K citations

    26

    h-index

1–5