Concepedia
Nature · 1993 · 1.9K citations · 19 references
ChromatinEpigenetic ChangeGeneticsDna MethylationEpigenomicsMolecular BiologyMedicineEpigenetics
19
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
Analytical Biochemistry · 1987 · 63.2K citations
Nucleic Acid Chemistry, Engineering, Natural Sciences +7
Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
Douglas A. Melton, Paul A. Krieg, Michael R. Rebagliati et al. · Nucleic Acids Research · 1984 · 6.4K citations · Full text
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 3.9K citations
Developmental Biology, Embryonic Lethality, Epigenetic Change +8
Parental imprinting of the mouse insulin-like growth factor II gene
Thomas M. DeChiara, Elizabeth J. Robertson, Argiris Efstratiadis · Cell · 1991 · 1.8K citations
Knockout Mouse, Developmental Biology, Growth Hormone +7
Completion of mouse embryogenesis requires both the maternal and paternal genomes
James McGrath, Davor Solter · Cell · 1984 · 1.6K citations · Full text
Biology, Developmental Biology, Fertility +12