MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

Suzanne J. Baker, Sanford D. Markowitz, Eric R. Fearon et al. · Science · 1990 · 1.8K citations

Wild-type P53, Oncology, Oncogenic Agent +13

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA

Joe Lewis, Richard R. Meehan, William J. Henzel et al. · Cell · 1992 · 1.4K citations

Chromatin, Chromatin Remodeling, Epigenetic Change +12

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

Joan Boyes, Adrian Bird · Cell · 1991 · 726 citations

Histone Modifications, Chromatin, Transcriptional Regulation +12

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

Richard R. Meehan, Joe Lewis, Stewart McKay et al. · Cell · 1989 · 657 citations

Chromatin, Medicine, Genetics +12

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

Yahli Lorch, J W LaPointe, Roger D. Kornberg · Cell · 1987 · 613 citations

Chromatin, Transcriptional Regulation, Developmental Biology +13