Concepedia

Yuan-Ta Lin

YL

9

Publications

2.9K

Citations

9

H-Index

2016

Active since

Affiliations

Massachusetts Institute of Technology(Current)

Harvard University

Broad Institute

Emory University

Rush University Medical Center

Yuan-Ta Lin is an author at Massachusetts Institute of Technology specializing in medicine, cell biology, and alzheimer's disease.

Top concepts

MedicineNeurologyCell BiologyNeuroscienceAlzheimer's DiseaseNeurodegenerative DiseasesCell PhysiologyNeurodegenerationNeuroinflammationStem Cell Research

Publications per year

2016–2022

9

Publications

9

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

Yuan-Ta Lin, Jinsoo Seo, Fan Gao et al. · Neuron · 2018 · 1.1K citations · Full text

Cellular Alterations Associated, Neurodegenerative Diseases, Neurobiology Of Disease +14

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

Waseem Raja, Alison E. Mungenast, Yuan-Ta Lin et al. · PLoS ONE · 2016 · 559 citations · Full text

Cerebral Organoid, Neurochemical Biomarkers, Amyloid Precursor Protein +22

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Joel Blanchard, Leyla Anne Akay, José Dávila-Velderrain et al. · Nature · 2022 · 460 citations · Full text

Oxysterol, Physiology, Degenerative Pathology +6

Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

Joel Blanchard, Michael Bula, José Dávila-Velderrain et al. · Nature Medicine · 2020 · 283 citations · Full text

Human Blood–brain Barrier, Blood–brain Barrier, Immunology +10

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia

Jinsoo Seo, Oleg Kritskiy, L. Ashley Watson et al. · Journal of Neuroscience · 2017 · 160 citations · Full text

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