Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

Johanna K. Hansen, Alina Baum, Kristen E. Pascal, +44

Science

VaccinationHumanized MiceSpike ProteinVaccine TargetViral Pathogenesis +13

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

Yuan-Ta Lin, Jinsoo Seo, Fan Gao, +18

Neuron

Cellular Alterations AssociatedNeurodegenerative DiseasesNeurobiology Of DiseaseMolecular NeuroscienceAlzheimer's Disease +12

Genome-wide remodeling of the epigenetic landscape during myogenic differentiation

Patrik Asp, Roy Blum, Vasupradha Vethantham, +6

Proceedings of the National Academy of Sciences

A Role for H3K4 Monomethylation in Gene Repression and Partitioning of Chromatin Readers

Jemmie Cheng, Roy Blum, Christopher Bowman, +4

Molecular Cell

Histone ModificationsChromatinChromatin RemodelingNatural SciencesGenetics +13

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior

Alexi Nott, Jemmie Cheng, Fan Gao, +9

Nature Neuroscience

Histone Deacetylase 3ChromatinTranscriptional RegulationSystems BiologyChromatin Structure +10

The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons

Hidekuni Yamakawa, Jemmie Cheng, Jay Penney, +7

Cell Reports

Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration

Gwyneth Welch, Carles A. Boix, Eloi Schmauch, +11

Science Advances

Dna Double-strand BreaksImmunologyImmune RegulationCell DeathNeuroinflammation +19

The Mammalian Sin3 Proteins Are Required for Muscle Development and Sarcomere Specification

Chris van Oevelen, Christopher Bowman, Jessica Pellegrino, +9

Molecular and Cellular Biology

Muscle FunctionCytoskeletonMuscle DevelopmentEpigeneticsCellular Physiology +23

Cell type-specific histone acetylation profiling of Alzheimer’s disease subjects and integration with genetics

Easwaran Ramamurthy, Gwyneth Welch, Jemmie Cheng, +5

Frontiers in Molecular Neuroscience

Evaluation of the binding orientations of testosterone in the active site of homology models for CYP2C11 and CYP2C13

Hongwu Wang, Jemmie Cheng, Diana Montgomery, +1

Biochemical Pharmacology

Molecular PharmacologyHomology ModelsSignal TransductionEndocrine MechanismHormonal Receptor +6