COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

Uğur Şahin, Alexander Muik, Evelyna Derhovanessian, +39

Nature

VaccinologyVaccinationVaccine DevelopmentHuman AntibodyImmunology +5

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

Alina Baum, Benjamin O. Fulton, Elzbieta Wloga, +13

Science

VaccinationViral EvolutionSpike ProteinAntibody ResistanceMedicine +12

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

Johanna K. Hansen, Alina Baum, Kristen E. Pascal, +44

Science

VaccinationHumanized MiceSpike ProteinVaccine TargetViral Pathogenesis +13

Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant

Leonid Yurkovetskiy, Xue Wang, Kristen E. Pascal, +19

Cell

Virus StructureSignal TransductionViral PathogenesisMolecular BiologyVirology +6

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Uğur Şahin, Alexander Muik, Isabel Vogler, +46

Nature

VaccinationBnt162b2 Vaccine InducesAllergyImmunologyTherapeutic Vaccine +7

The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies

Richard Copin, Alina Baum, Elzbieta Wloga, +34

Cell

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

Kristen E. Pascal, Christopher M. Coleman, Alejandro O. Mujica, +17

Proceedings of the National Academy of Sciences

Viral DiagnosticsImmunologyViral PathogenesisImmunotherapeuticsTraditional Approaches +16

Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates

Kristen E. Pascal, Drew Dudgeon, John C. Trefry, +38

The Journal of Infectious Diseases

BNT162b2 induces SARS-CoV-2-neutralising antibodies and T cells in humans

Uğur Şahin, Alexander Muik, Isabel Vogler, +46

Humoral ResponseImmunologyImmunodominanceT CellsCovid-19 +15

Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis

Erika Libby, Kristen E. Pascal, Eli Mordechai, +2

Microbes and Infection

Host ResponseAtopobium Vaginae TriggersPathogenesisImmunologyInnate Immune System +8