Concepedia

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt

Jinfang Zhang, Kai Xu, Pengda Liu, Yan Geng, Bin Wang, Wenjian Gan, Jianping Guo, Fei Wu, Y. Rebecca Chin, Christian Berrios,

Molecular Cell · 2016 · 107 citations · 37 references

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37

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

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mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali et al. · Cell · 2002 · 3K citations · Full text

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The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Yasemin Sancak, Timothy R. Peterson, Yoav D. Shaul et al. · Science · 2008 · 2.8K citations

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Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Brendan D. Manning, Andrew R. Tee, M. Nicole Logsdon et al. · Molecular Cell · 2002 · 1.6K citations · Full text

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Regulation of TORC1 by Rag GTPases in nutrient response

Eunjung Kim, Pankuri Goraksha-Hicks, Li Li et al. · Nature Cell Biology · 2008 · 1.3K citations · Full text

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