Yasemin Sancak

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Yasemin Sancak, Timothy R. Peterson, Yoav D. Shaul et al. · Science · 2008 · 2.7K citations · Full text

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Yasemin Sancak, Liron Bar‐Peled, Roberto Zoncu et al. · Cell · 2010 · 2.4K citations · Full text

Protein Function, Molecular Physiology, Signal Transduction +14

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Joshua M. Baughman, Fabiana Perocchi, Hany S. Girgis et al. · Nature · 2011 · 1.9K citations · Full text

Molecular Physiology, Mitochondrial Function, Natural Sciences +9

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H ⁺ -ATPase

Roberto Zoncu, Liron Bar‐Peled, Alejo Efeyan et al. · Science · 2011 · 1.6K citations · Full text

Lysosomal Amino Acids, Molecular Biology, Mtor Pathway +20

PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase

Yasemin Sancak, Carson C. Thoreen, Timothy R. Peterson et al. · Molecular Cell · 2007 · 1.2K citations · Full text

Signal Transduction, Signaling Pathway, Natural Sciences +9