Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Joshua M. Baughman, Fabiana Perocchi, Hany S. Girgis, +9

Nature

Molecular PhysiologyMitochondrial FunctionNatural SciencesGeneticsDna Replication +7

Bidirectional promoters generate pervasive transcription in yeast

Zhenyu Xu, Wu Wei, Julien Gagneur, +7

Nature

Transcriptional RegulationGeneticsBidirectional PromotersGene RegulationYeast +4

MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake

Fabiana Perocchi, Vishal M. Gohil, Hany S. Girgis, +4

Nature

Signal TransductionMitochondrial FunctionCell SignalingNatural SciencesMolecular Biology +7

K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

Christina J. Groß, Ritu Mishra, Katharina S. Schneider, +24

Immunity

InflammationSignal TransductionSignaling PathwayMitochondrial FunctionNatural Sciences +9

MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter

György Csordás, Tünde Golenár, Erin L. Seifert, +11

Cell Metabolism

Micu1 Controls BothSignal TransductionMolecular PhysiologyMitochondrial FunctionCooperative Activation +9

Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway

Cathleen Holze, Chloé Michaudel, Claire Mackowiak, +13

Nature Immunology

Signal TransductionNecroptosisApoptosisCell DeathPathology +7

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

Vishal M. Gohil, Sunil A. Sheth, Roland Nilsson, +8

Nature Biotechnology

Energy MetabolismMitochondrial FunctionBiochemistryMedicinePhysiology +9

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

Caroline Fecher, Laura Trovò, Stephan A. Müller, +15

Nature Neuroscience

Neurodegenerative DiseasesMolecular NeuroscienceMitochondrial FunctionCell-type-specific ProfilingNeurochemical Biomarkers +6

Antisense artifacts in transcriptome microarray experiments are resolved by actinomycin D

Fabiana Perocchi, Zhenyu Xu, Sandra Clauder‐Münster, +1

Nucleic Acids Research

Biomolecular ToolMolecular BiologyTranscriptomics TechnologyGene Expression ProfilingYeast +16

Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy

Angelika B. Harbauer, J. Tabitha Hees, Simone Wanderoy, +11

Neuron

MitophagyMolecular NeuroscienceSynaptojanin 2Mitochondrial FunctionOrganelle Dynamic +9