Alejo Efeyan

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H ⁺ -ATPase

Roberto Zoncu, Liron Bar‐Peled, Alejo Efeyan et al. · Science · 2011 · 1.6K citations · Full text

Lysosomal Amino Acids, Molecular Biology, Mtor Pathway +20

Senescence in premalignant tumours

Manuel Collado, Jesús Gil, Alejo Efeyan et al. · Nature · 2005 · 1.4K citations · Full text

Tumoral Pathology, Medicine, Pathology +4

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival

Alejo Efeyan, Roberto Zoncu, Steven H. Chang et al. · Nature · 2012 · 443 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +10

mTOR and cancer: many loops in one pathway

Alejo Efeyan, David M. Sabatini · Current Opinion in Cell Biology · 2009 · 415 citations

Tumor Biology, Medicine, Cancer Genomics +5

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

Ana Ortega-Molina, Alejo Efeyan, Elena Lopez-Guadamillas et al. · Cell Metabolism · 2012 · 342 citations · Full text

Obesity, Metabolic Syndrome, Energy Homeostasis +11