Concepedia

Senescence in premalignant tumours

Manuel Collado, Jesús Gil, Alejo Efeyan, Carmen Guerra, Alberto J. Schuhmacher, Marta Barradas, Alberto Benguría, Ángel Zaballos, Juana M. Flores, Mariano Barbacid,

Nature · 2005 · 1.5K citations · 5 references

DOI

Concepts

References

5

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence

Masashi Narita, Sabrina Nuñez, Édith Heard et al. · Cell · 2003 · 2.2K citations · Full text

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Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects

David A. Tuveson, Alice T. Shaw, Nicholas A. Willis et al. · Cancer Cell · 2004 · 816 citations · Full text

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Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

Carmen Guerra, Nieves Mijimolle, Alma Dhawahir et al. · Cancer Cell · 2003 · 572 citations · Full text

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