Concepedia

Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence

Masashi Narita, Sabrina Nuñez, Édith Heard, Masako Narita, Athena W. Lin, Stephen Hearn, David L. Spector, Gregory J. Hannon, Scott W. Lowe

Cell · 2003 · 2.2K citations · 43 references

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43

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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The limited in vitro lifetime of human diploid cell strains

Leonard Hayflick · Experimental Cell Research · 1965 · 5.8K citations

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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

Andrew J. Bannister, Philip Zegerman, Janet F. Partridge et al. · Nature · 2001 · 2.9K citations

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

Monika Lachner, Dónal O’Carroll, Stephen Rea et al. · Nature · 2001 · 2.8K citations

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