The Rb-E2F Regulatory Network is a molecular signaling network that governs the transition from the G1 to the S phase of the cell cycle by reversibly inhibiting the E2F family of transcription factors through the retinoblastoma protein (Rb) in response to cellular and environmental cues.
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106
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
Masashi Narita, Sabrina Nuñez, Édith Heard et al. · Cell · 2003 · 2.2K citations · Full text
E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins
Joseph R. Nevins · Science · 1992 · 1.5K citations
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Case Western Reserve University
Cleveland, United States
7 h-index
24 publications
2K citations
Howard Hughes Medical Institute
Chevy Chase, United States
5 h-index
14 publications
4.5K citations
Duke Medical Center
Durham, United States
4 h-index
11 publications
2K citations
Sidney Kimmel Cancer Center
Philadelphia, United States
4 h-index
27 publications
1K citations
Massachusetts General Hospital
Boston, United States
4 h-index
17 publications
3.9K citations
Cold Spring Harbor Laboratory
Cold Spring Harbor, United States
4 h-index
18 publications
21.2K citations
University of Ottawa
Ottawa, Canada
4 h-index
20 publications
944 citations
University of Illinois Chicago
Chicago, United States
4 h-index
8 publications
1.1K citations
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- Molecular and Cellular Biology
MCB · 10 publications · 960 citations
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- Oncogene
8 publications · 454 citations
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- Cell Cycle
5 publications · 155 citations
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- The EMBO Journal
5 publications · 462 citations
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- Journal of Biological Chemistry
JBC · 4 publications · 345 citations
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