Yoav D. Shaul

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Yasemin Sancak, Timothy R. Peterson, Yoav D. Shaul et al. · Science · 2008 · 2.8K citations

Life Sciences, Cell Biology, Molecular Biology +14

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Richard Possemato, Kevin M. Marks, Yoav D. Shaul et al. · Nature · 2011 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Michael E. Pacold, Kyle R. Brimacombe, Sze Ham Chan et al. · Nature Chemical Biology · 2016 · 589 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +14

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Maik Luu, Sabine Pautz, Vanessa Kohl et al. · Nature Communications · 2019 · 517 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

Yoav D. Shaul, Elizaveta Freinkman, William C. Comb et al. · Cell · 2014 · 231 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12