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Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor

Jacques Dumas, Holia Hatoum‐Mokdad, Robert Sibley, Roger A. Smith, William J. Scott, Uday R. Khire, Wendy Lee, Jill E. Wood, Donald J. Wolanin, Jeffrey Cooley,

Bioorganic & Medicinal Chemistry Letters · 2002 · 22 citations · 5 references

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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

Christopher Pargellis, Liang Tong, Laurie Churchill et al. · Nature Structural Biology · 2002 · 834 citations · Full text

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Pharmacological Effects of SB 220025, a Selective Inhibitor of P38 Mitogen-Activated Protein Kinase, in Angiogenesis and Chronic Inflammatory Disease Models

Jeffrey R. Jackson, Brian Bolognese, Leonard M. Hillegass et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 174 citations

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Involvement of p38 MAP kinase in TGF‐β‐stimulated VEGF synthesis in aortic smooth muscle cells

Takuji Yamamoto, Osamu Kozawa, Kumiko Tanabe et al. · Journal of Cellular Biochemistry · 2001 · 54 citations

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Discovery of a new class of p38 kinase inhibitors

Jacques Dumas, Robert Sibley, Bernd Riedl et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 47 citations · Full text

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p38 Kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas

Anikó M. Redman, Jeffrey S. Johnson, Robert Dally et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 44 citations · Full text

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