Bernd Riedl

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

Scott M. Wilhelm, Christopher Carter, LiYa Tang et al. · Cancer Research · 2004 · 4K citations · Full text

Medicine, Oncology, Pharmacology +17

Combined Tyrosine and Serine/Threonine Kinase Inhibition by Sorafenib Prevents Progression of Experimental Pulmonary Hypertension and Myocardial Remodeling

Martina I. Klein, Ralph T. Schermuly, Peter Ellinghaus et al. · Circulation · 2008 · 154 citations · Full text

Medicine, Cardiology, Pharmacology +17

The Novel α7 Nicotinic Acetylcholine Receptor Agonist N-[(3 R)-1-Azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide Improves Working and Recognition Memory in Rodents

Frank Boess, Jean De Vry, Christina Erb et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 139 citations

Medicine, Neuroscience, Pharmacology +17

Diastereoselective Formation of (<i>Z</i>)-Didehydroamino Acid Esters

Ulrich Schmidt, Volker Leitenberger, Albrecht Lieberknecht et al. · Synthesis · 1992 · 123 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +8

A Scaleable Synthesis of BAY 43-9006:  A Potent Raf Kinase Inhibitor for the Treatment of Cancer

Donald Bankston, Jacques Dumas, Reina Natero et al. · Organic Process Research & Development · 2002 · 112 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11