Roger A. Smith

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

Allen Krantz, Leslie J. Copp, Peter J. Coles et al. · Biochemistry · 1991 · 143 citations

Life Sciences, Biochemistry, Pharmacology +17

Efficient .alpha.-halogenation of acyl chlorides by N-bromosuccinimide, N-chlorosuccinimide, and molecular iodine

David N. Harpp, Catherine J. Black, John G. Gleason et al. · The Journal of Organic Chemistry · 1975 · 100 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Roger A. Smith, J A Barbosa, Cheri L. Blum et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 85 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Organic sulfur chemistry. 42. Sulfur-sulfur bond cleavage processes. Selective desulfurization of trisulfides

David N. Harpp, Roger A. Smith · Journal of the American Chemical Society · 1982 · 80 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

New inhibitors of cysteine proteinases. Peptidyl acyloxymethyl ketones and the quiescent nucleofuge strategy

Roger A. Smith, Leslie J. Copp, Peter J. Coles et al. · Journal of the American Chemical Society · 1988 · 65 citations

Life Sciences, Biochemistry, Chemistry +12