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Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Combinatorial ChemistryMedicinal ChemistryDrug TargetBioorganic ChemistryBiochemistrySecond Generation LeadNatural SciencesMedicineRational Drug DesignRaf Kinase InhibitorsNew ClassChemical BiologyPharmacologyPharmaceutical ChemistryDrug Discovery