Craig M. Crews

Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation

Kathleen M. Sakamoto, Kyung B. Kim, Akiko Kumagai et al. · Proceedings of the National Academy of Sciences · 2001 · 2.3K citations · Full text

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson, Alina Mares, Ian E. Smith et al. · Nature Chemical Biology · 2015 · 1.3K citations · Full text

Biochemistry, Protein Assembly, Natural Sciences +2

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Jing Lü, Yimin Qian, Martha Altieri et al. · Chemistry & Biology · 2015 · 1.1K citations · Full text

Natural Sciences, Molecular Biology, Dna Replication +3

The Primary Structure of MEK, a Protein Kinase that Phosphorylates the <i>ERK</i> Gene Product

Craig M. Crews, Alessandro Alessandrini, Raymond L. Erikson · Science · 1992 · 928 citations

Epoxomicin, a potent and selective proteasome inhibitor, exhibits<i>in vivo</i>antiinflammatory activity

Lihao Meng, Royce Mohan, Benjamin H. Kwok et al. · Proceedings of the National Academy of Sciences · 1999 · 927 citations