Daniel P. Bondeson

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson, Alina Mares, Ian E. Smith et al. · Nature Chemical Biology · 2015 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +9

Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

Daniel P. Bondeson, Blake E. Smith, George M. Burslem et al. · Cell chemical biology · 2017 · 901 citations · Full text

Engineering, Bioengineering, Biomolecular Engineering +13

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

George M. Burslem, Blake E. Smith, Ashton C. Lai et al. · Cell chemical biology · 2017 · 673 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation

George M. Burslem, Anna Reister Schultz, Daniel P. Bondeson et al. · Cancer Research · 2019 · 222 citations

Medicine, Molecular Biology, Oncology +14

Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer

Daniel P. Bondeson, Brenton R. Paolella, Adhana Asfaw et al. · Nature Cancer · 2022 · 76 citations · Full text

Medicine, Molecular Biology, Oncology +11