George M. Burslem - Concepedia

Author

George M. Burslem

University of Pennsylvania ORCID

Also Known As

Burslem, George M., George M. Burslem, George Burslem, George M Burslem, George M. Burslem, Ophir Shalem

108

Publications

4.3K

Citations

H-Index

Concepts

All Affiliations

University of Pennsylvania University of Leeds Institute of Structural and Molecular Biology Yale University Children's Hospital of Philadelphia

About

George M. Burslem is an author at University of Pennsylvania specializing in medicine, natural sciences, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	995
2	Natural Sciences	11	11	1K
3	Biochemistry	8	8	980
4	Engineering	3	3	111
5	Social Sciences	1	1	16

George M. Burslem

Publications

2.9K

Citations

H-Index

Page 1

	Year	Citations
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead Daniel P. Bondeson, Blake E. Smith, George M. Burslem, Cell chemical biology Protac DesignSelective DegradationBiomolecular EngineeringPromiscuous Warhead	2017	867
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study George M. Burslem, Blake E. Smith, Ashton C. Lai, Cell chemical biology Protein ChemistryProtein FunctionBiochemistryProtein FoldingNatural Sciences	2017	643
Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation George M. Burslem, Anna Reister Schultz, Daniel P. Bondeson, Cancer Research	2019	213
Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion George M. Burslem, Jayoung Song, Xin Chen, Journal of the American Chemical Society Chemical BiologyPharmaceutical ChemistryTumor BiologyMedicinal ChemistryReceptor Tyrosine Kinase	2018	168
Double quick, double click reversible peptide “stapling” Claire M. Grison, George M. Burslem, Jennifer A. Miles, Chemical Science	2017	101
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation Michael Grasso, Gavin J. Bond, Ye‐Jin Kim, Journal of Biological Chemistry	2021	72
Small‐Molecule Proteomimetic Inhibitors of the HIF‐1α–p300 Protein–Protein Interaction George M. Burslem, Hannah F. Kyle, Alexander L. Breeze, ChemBioChem	2014	68
Click-enabled heterotrifunctional template for sequential bioconjugations David M. Beal, Victoria E. Albrow, George M. Burslem, Organic & Biomolecular Chemistry Bioorganic ChemistryEngineeringClick ChemistriesSequential BioconjugationsPeptide Engineering	2011	59
A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds Thomas James, Paul MacLellan, George M. Burslem, Organic & Biomolecular Chemistry	2014	53
Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure–Degradation Relationships George M. Burslem, Philipp Ottis, Saul Jaime‐Figueroa, ChemMedChem	2018	52

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