Concepedia

Blake E. Smith

BE

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Publications

5

Citations

2.3K

H-Index

5

Active since

2017

Affiliations

Arvinas (United States)(Current)

Yale University

Blake E. Smith is an author at Arvinas (United States) specializing in medicine, biomolecular engineering, and molecular oncology.

Top concepts

MedicineBiomolecular EngineeringHealthVirologyImmunologyProteomicsVaccinationBiochemistryCell BiologyPathogenesis

Publications per year

2017–2022

5

Publications

5

Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

Daniel P. Bondeson, Blake E. Smith, George M. Burslem et al. · Cell chemical biology · 2017 · 867 citations · Full text

Protac Design, Selective Degradation, Biomolecular Engineering +1

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

George M. Burslem, Blake E. Smith, Ashton C. Lai et al. · Cell chemical biology · 2017 · 643 citations · Full text

Protein Chemistry, Protein Function, Biochemistry +14

Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase

Blake E. Smith, Stephen L. Wang, Saul Jaime‐Figueroa et al. · Nature Communications · 2019 · 502 citations · Full text

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Jaya Sangodkar, Abbey Perl, Rita Tohmé et al. · Journal of Clinical Investigation · 2017 · 196 citations · Full text

Kras-driven Tumor Growth, Cell Proliferation, Cancer Biology +18

Antigen identification and high-throughput interaction mapping by reprogramming viral entry

Connor S. Dobson, Anna N. Reich, Stephanie Gaglione et al. · Nature Methods · 2022 · 103 citations · Full text

Vaccination, Viral Evolution, Molecular Virology +9

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