Joseph F. Johnston

Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase

Brett P. Monia, Joseph F. Johnston, Thomas Geiger et al. · Nature Medicine · 1996 · 451 citations

Phosphorothioate Antisense, C-raf Kinase, Antitumor Activity +9

Destabilization of Raf-1 by Geldanamycin Leads to Disruption of the Raf-1–MEK–Mitogen-Activated Protein Kinase Signalling Pathway

Theodor W. Schulte, Mikhail V. Blagosklonny, L.Y. Romanova et al. · Molecular and Cellular Biology · 1996 · 275 citations · Full text

Molecular Regulation, Molecular Biology, Tumor Biology +16

Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides.

Brett P. Monia, Joseph F. Johnston, David J. Ecker et al. · Journal of Biological Chemistry · 1992 · 260 citations · Full text

Oligonucleotide Length, Molecular Biology, Antisense Therapy +16

Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

Prisca Honoré, Karen Kage, Joseph P. Mikusa et al. · Pain · 2002 · 235 citations

Chronic Inflammatory, Acute Pain, Pain Medicine +18

Nuclease Resistance and Antisense Activity of Modified Oligonucleotides Targeted to Ha-

Brett P. Monia, Joseph F. Johnston, Henri Sasmor et al. · Journal of Biological Chemistry · 1996 · 177 citations · Full text