Theodor W. Schulte - Concepedia

Author

Theodor W. Schulte

National Cancer Institute

Also Known As

T W Schulte, Theodor Schulte, Theodor W Schulte, Theodor W. Schulte

Publications

3.6K

Citations

H-Index

Concepts

All Affiliations

National Cancer Institute National Institutes of Health National Institutes of Health Clinical Center Kyowa Kirin (Japan)Mayo Clinic

About

Theodor W. Schulte is an author at National Cancer Institute specializing in medicine, natural sciences, and tumor biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	2.5K
2	Natural Sciences	7	7	1.9K
3	Cell Biology	5	5	695
4	Biochemistry	3	3	914
5	Chemical Biology	1	1	154

Theodor W. Schulte

Publications

3.3K

Citations

H-Index

Page 1

	Year	Citations
The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation James P. Grenert, W. Patrick Sullivan, Patrick Fadden, Journal of Biological Chemistry Crystal StructureProtein AssemblyAtp/adp Switch DomainMolecular RegulationMolecular Biology	1997	568
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin Theodor W. Schulte, Leonard Μ. Neckers Cancer Chemotherapy and Pharmacology Medicinal ChemistryMedicineNatural Sciences17-Allylamino-17-demethoxygeldanamycin BindsAntibiotic Adjuvant	1998	475
Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association Theodor W. Schulte, Mikhail V. Blagosklonny, Christian Ingui, Journal of Biological Chemistry	1995	455
Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin Theodor W. Schulte, Shiro Akinaga, Shiro Soga, Cell Stress and Chaperones MedicineN-terminal DomainMolecular BiologyAntibiotic Radicicol BindsPharmacology	1998	399
Destabilization of Raf-1 by Geldanamycin Leads to Disruption of the Raf-1–MEK–Mitogen-Activated Protein Kinase Signalling Pathway Theodor W. Schulte, Mikhail V. Blagosklonny, L.Y. Romanova, Molecular and Cellular Biology Molecular RegulationMolecular BiologyTumor BiologySignaling PathwayCell Regulation	1996	275
The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome. Won Gun An, Theodor W. Schulte, Leonard Μ. Neckers PubMed	2000	270
Geldanamycin-Induced Destabilization of Raf-1 Involves the Proteasome Theodor W. Schulte, Won Gun An, Leonard Μ. Neckers Biochemical and Biophysical Research Communications BiochemistryNatural SciencesAnti-cancer AgentGeldanamycin-induced DestabilizationCellular Biochemistry	1997	192
Interaction of Radicicol with Members of the Heat Shock Protein 90 Family of Molecular Chaperones Theodor W. Schulte, Shiro Akinaga, T. Murakata, Molecular Endocrinology Drug TargetProtein AssemblyHsp90 AlphaMolecular BiologyChemical Biology	1999	154
Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo Luke Whitesell, Patrick D. Sutphin, Wen G An, Oncogene Tumor BiologyCell RegulationMedicineNatural SciencesMolecular Biology	1997	126
Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G1 phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex Yukimasa Shiotsu, Leonard Μ. Neckers, Ivo Wortman, Blood	2000	100

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