Leonard Μ. Neckers - Concepedia

Author

Leonard Μ. Neckers

Also Known As

L M Neckers, LEONARD M. NECKERS, LEONARD NECKERS, Leonard M Neckers, Leonard M. Neckers, Leonard Neckers, Leonard Μ. Neckers

292

Publications

10.4K

Citations

H-Index

142

Concepts

All Affiliations

National Cancer Institute National Institutes of Health Center for Cancer Research Frederick National Laboratory for Cancer Research National Center for Advancing Translational Sciences

LΜ

About

Leonard Μ. Neckers is an author at National Cancer Institute specializing in medicine, cell biology, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	32	49	5.8K
2	Natural Sciences	15	17	2.9K
3	Social Sciences	7	7	364
4	Health Sciences	4	4	227
5	Engineering	1	1	111

Leonard Μ. Neckers

Publications

10K

Citations

H-Index

Page 1

	Year	Citations
Stabilization of wild-type p53 by hypoxia-inducible factor 1α Won Gun An, Meera Kanekal, Michel Simon, Nature Cancer ResearchRedox RegulatorHypoxia (Medicine)Hypoxia-inducible Factor 1αCell Death	1998	819
A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1 Reino Heikkilä, G Schwab, Eric Wickstrom, Nature Molecular PhysiologySignal TransductionMolecular RegulationNatural SciencesOligonucleotide	1987	691
Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway Jennifer S. Isaacs, Yunjin Jung, Edward G. Mimnaugh, Journal of Biological Chemistry	2002	651
The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation James P. Grenert, W. Patrick Sullivan, Patrick Fadden, Journal of Biological Chemistry Crystal StructureProtein AssemblyAtp/adp Switch DomainMolecular RegulationMolecular Biology	1997	568
The Heat Shock Protein 90 Antagonist Novobiocin Interacts with a Previously Unrecognized ATP-binding Domain in the Carboxyl Terminus of the Chaperone Monica G. Marcu, Ahmed Chadli, Ilham Bouhouche, Journal of Biological Chemistry	2000	503
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin Theodor W. Schulte, Leonard Μ. Neckers Cancer Chemotherapy and Pharmacology Medicinal ChemistryMedicineNatural Sciences17-Allylamino-17-demethoxygeldanamycin BindsAntibiotic Adjuvant	1998	475
Novobiocin and Related Coumarins and Depletion of Heat Shock Protein 90-Dependent Signaling Proteins Monica G. Marcu, T W Schulte, Leonard Μ. Neckers JNCI Journal of the National Cancer Institute	2000	402
Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin Theodor W. Schulte, Shiro Akinaga, Shiro Soga, Cell Stress and Chaperones MedicineN-terminal DomainMolecular BiologyAntibiotic Radicicol BindsPharmacology	1998	399
Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis Soichiro Yoshida, Shinji Tsutsumi, Guillaume Mühlebach, Proceedings of the National Academy of Sciences	2013	293
Destabilization of Raf-1 by Geldanamycin Leads to Disruption of the Raf-1–MEK–Mitogen-Activated Protein Kinase Signalling Pathway Theodor W. Schulte, Mikhail V. Blagosklonny, L.Y. Romanova, Molecular and Cellular Biology Molecular RegulationMolecular BiologyTumor BiologySignaling PathwayCell Regulation	1996	275

Page 1