Jennifer S. Isaacs

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Jennifer S. Isaacs, Yun Jin Jung, David R. Mole et al. · Cancer Cell · 2005 · 942 citations · Full text

Medicine, Biochemistry, Oncology +13

IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis

Yunjin Jung, Jennifer S. Isaacs, Sunmin Lee et al. · The FASEB Journal · 2003 · 675 citations

Medicine, Cancer Biology, Oncology +17

Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway

Jennifer S. Isaacs, Yunjin Jung, Edward G. Mimnaugh et al. · Journal of Biological Chemistry · 2002 · 659 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance

Himisha Beltran, Andrew M. Hruszkewycz, Howard I. Scher et al. · Clinical Cancer Research · 2019 · 394 citations · Full text

Medicine, Oncology, Urology +17

Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity

Edward G. Mimnaugh, Wanping Xu, Michele D. Vos et al. · Molecular Cancer Therapeutics · 2004 · 211 citations · Full text

Medicine, Oncology, Pharmacology +15