Mark A. Bobko

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Roger A. Smith, J A Barbosa, Cheri L. Blum et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 85 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Drug Target +12

Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors

Jesús R. Medina, Christopher Becker, Charles W. Blackledge et al. · Journal of Medicinal Chemistry · 2011 · 53 citations · Full text

Drug Target, Chemoprevention Strategy, Chemical Biology +20

Solid-phase synthesis of a library of piperazinediones and diazepinediones via kaiser oxime resin

Roger A. Smith, Mark A. Bobko, Wendy Lee · Bioorganic & Medicinal Chemistry Letters · 1998 · 51 citations

Combinatorial Chemistry, Chemical Engineering, Solid-phase Synthesis +7

Discovery and SAR of novel Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK)

Charles L. Cywin, Baoping Zhao, Daniel W. McNeil et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 48 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Drug Target +12

Discovery of a new class of p38 kinase inhibitors

Jacques Dumas, Robert Sibley, Bernd Riedl et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 47 citations · Full text

Medicinal Chemistry, Drug Target, P38 Kinase Inhibitors +5