Jesús R. Medina - Concepedia

Author

Jesús R. Medina

Also Known As

J. MEDINA, J. Medina, J. R. MEDINA, J. R. Medina, J.R. Medina, Jersinho Medina, Jesus Medina, Jesus R. Medina, Jesús R. Medina, Medina, J.R.

Publications

1.3K

Citations

H-Index

Concepts

All Affiliations

GlaxoSmithKline (United States)University of Puerto Rico at Río Piedras Research Triangle Park Foundation

About

Jesús R. Medina is an author at GlaxoSmithKline (United States) specializing in pharmacology, natural sciences, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	6	6	995
2	Medicine	5	5	929
3	Biochemistry	5	5	976
4	Engineering	2	2	98
5	Biomolecular Engineering	1	1	601

Jesús R. Medina

Publications

1.2K

Citations

H-Index

Page 1

	Year	Citations
Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1<i>H</i>-indol-5-yl)-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK) Jeffrey M. Axten, Jesús R. Medina, Yanhong Feng, Journal of Medicinal Chemistry Chemoprevention StrategyChemical BiologyPharmaceutical ChemistryTumor BiologyMolecular Pharmacology	2012	601
Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development Jeffrey M. Axten, Stuart P. Romeril, Arthur Y. L. Shu, ACS Medicinal Chemistry Letters Drug Discovery ProgramTumor BiologyPhysical PropertiesMedicinal ChemistrySignaling Pathway	2013	224
Multigram Synthesis of the C29−C51 Subunit and Completion of the Total Synthesis of Altohyrtin C (Spongistatin 2) Clayton H. Heathcock, Mark McLaughlin, Jesús R. Medina, Journal of the American Chemical Society Bioorganic ChemistryEngineeringMolecular BiologyOrganic ChemistryHeterocycle Chemistry	2003	83
9-Borabicyclo[3.3.2]decanes and the Asymmetric Hydroboration of 1,1-Disubstituted Alkenes Ana Z. González, José G. Román, Eduvigis González, Journal of the American Chemical Society	2008	79
Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors Jesús R. Medina, Christopher Becker, Charles W. Blackledge, Journal of Medicinal Chemistry Drug TargetChemoprevention StrategyChemical BiologyMedicinal ChemistryDrug Design	2011	53
Selective 3-Phosphoinositide-Dependent Kinase 1 (PDK1) Inhibitors: Dissecting the Function and Pharmacology of PDK1 Jesús R. Medina Journal of Medicinal Chemistry Drug TargetPharmacotherapyAgc Kinase FamilySignaling PathwayReceptor Tyrosine Kinase	2013	32
Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery Jesús R. Medina, Charles W. Blackledge, Dirk A. Heerding, ACS Medicinal Chemistry Letters	2010	30
New Δ<sup>5,9</sup> Fatty Acids in the Phospholipids of the Sea Anemone Stoichactis helianthus Néstor M. Carballeira, Jesús R. Medina Journal of Natural Products	1994	30
Mono- and dialkylborane reagents from silylamine-boranes John A. Soderquist, Ramon Huertas, Jesús R. Medina Tetrahedron Letters Dialkylborane ReagentsOrganic ChemistryStereoselective SynthesisHeterocycle ChemistryChemistry	1998	23
Novel hydroborating agents from silylamine-boranes John A. Soderquist, Jesús R. Medina, Ramon Huertas Tetrahedron Letters Organic ChemistryChemistryBorophene	1998	22

Page 1