Arthur Y. L. Shu

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1<i>H</i>-indol-5-yl)-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

Jeffrey M. Axten, Jesús R. Medina, Yanhong Feng et al. · Journal of Medicinal Chemistry · 2012 · 601 citations · Full text

Chemoprevention Strategy, Chemical Biology, Pharmaceutical Chemistry +24

Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development

Jeffrey M. Axten, Stuart P. Romeril, Arthur Y. L. Shu et al. · ACS Medicinal Chemistry Letters · 2013 · 224 citations · Full text

Drug Discovery Program, Tumor Biology, Physical Properties +18

Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites

Ellen E. Codd, Arthur Y. L. Shu, Richard F. Walker · Neuropharmacology · 1989 · 147 citations

Signal Transduction, Pituitary Binding Sites, Pituitary Gland +10

Some aspects of palladium-catalyzed reactions of aryl and vinylic halides with conjugated dienes in the presence of mild nucleophiles

J. M. O’Connor, Barbara J. Stallman, W. G. Clark et al. · The Journal of Organic Chemistry · 1983 · 109 citations

Chemical Engineering, Palladium-catalyzed Reactions, Engineering +12

Biosynthetic studies of marine lipids. 11. Synthesis, biosynthesis, and absolute configuration of the internally branched demospongic acid, 22-methyl-5,9-octacosadienoic acid

Daniel Raederstorff, Arthur Y. L. Shu, Janice E. Thompson et al. · The Journal of Organic Chemistry · 1987 · 85 citations

Marine Lipids, Lipid Analysis, Biosynthesis +15