Robert Sibley

A Scaleable Synthesis of BAY 43-9006:  A Potent Raf Kinase Inhibitor for the Treatment of Cancer

Donald Bankston, Jacques Dumas, Reina Natero et al. · Organic Process Research & Development · 2002 · 111 citations

Other Urea Targets, Medicinal Chemistry, Bioorganic Chemistry +15

Synthesis and structure activity relationships of novel small molecule cathepsin D inhibitors

Jacques Dumas, David R. Brittelli, Jinshan Chen et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 88 citations · Full text

Biochemistry, Natural Sciences, Medicine +7

1-Phenyl-5-pyrazolyl ureas: potent and selective p38 kinase inhibitors

Jacques Dumas, Holia Hatoum‐Mokdad, Robert Sibley et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 53 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, 1-Phenyl-5-pyrazolyl Ureas +6

Discovery of a new class of p38 kinase inhibitors

Jacques Dumas, Robert Sibley, Bernd Riedl et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 47 citations · Full text

Medicinal Chemistry, Drug Target, P38 Kinase Inhibitors +5

Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors

Uday R. Khire, Donald Bankston, J A Barbosa et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 44 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +5