Concepedia

Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors

Uday R. Khire, Donald Bankston, J A Barbosa, David R. Brittelli, Yolanda Caringal, Robert H. Carlson, Jacques Dumas, Todd Gane, Sarah L. Heald, Barbara Hibner,

Bioorganic & Medicinal Chemistry Letters · 2003 · 44 citations · 5 references

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References

5

The Rationale and Strategy Used to Develop a Series of Highly Potent, Irreversible, Inhibitors of the Epidermal Growth Factor Receptor Family of Tyrosine Kinases

A. J. Bridges · Current Medicinal Chemistry · 1999 · 101 citations

, , +17

The rationale and strategy used to develop a series of highly potent, irreversible, inhibitors of the epidermal growth factor receptor family of tyrosine kinases.

Bridges Aj · PubMed · 1999 · 88 citations

, , +17

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Roger A. Smith, J A Barbosa, Cheri L. Blum et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 85 citations · Full text

, , +17

Protein kinase inhibitors: emerging pharmacophores 1997 - 2000

Jacques Dumas · Expert Opinion on Therapeutic Patents · 2001 · 70 citations

, , +12

Drugs targeted against protein kinases

C. Chandra Kumar, Vincent Madison · Expert Opinion on Emerging Drugs · 2001 · 31 citations

, , +17