Orally Active Trifluoromethyl Ketone Inhibitors of Human Leukocyte Elastase

Chris A. Veale, Peter R Bernstein, Claudia Bohnert, +22

Journal of Medicinal Chemistry

Medicinal ChemistryOral BioavailabilityPharmaceutical ScienceBiochemistryHuman Leukocyte Elastase +11

Peptidyl .alpha.-ketoheterocyclic inhibitors of human neutrophil elastase. 2. Effect of varying the heterocyclic ring on in vitro potency

Philip D. Edwards, Donald J. Wolanin, Donald W. Andisik, +1

Journal of Medicinal Chemistry

Discovery and Biological Activity of Orally Active Peptidyl Trifluoromethyl Ketone Inhibitors of Human Neutrophil Elastase

Philip D. Edwards, Donald W. Andisik, Craig A. Bryant, +14

Journal of Medicinal Chemistry

Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors

Uday R. Khire, Donald Bankston, J A Barbosa, +23

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyBiochemistryMedicineRaf Kinase InhibitorsMechanism Of Action +3

Effect of synthetic metalloprotease inhibitors on cartilage autolysis in vitro.

C.B. Caputo, Linda A. Sygowski, Donald J. Wolanin, +5

Journal of Pharmacology and Experimental Therapeutics

Total synthesis of quadrone and terrecyclic acid A

Paul A. Wender, Donald J. Wolanin

The Journal of Organic Chemistry

AltmetricsInformationAltmetric Attention ScoreChemometricsTotal Synthesis +9

Synthesis of polyfluoroaryl [2.2] cyclophanes

Robert Filler, Garry L. Cantrell, Donald J. Wolanin, +1

Journal of Fluorine Chemistry

HeterocyclicFluorous SynthesisOrganic ChemistryChemistryHeterocycle Chemistry

Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor

Jacques Dumas, Holia Hatoum‐Mokdad, Robert Sibley, +27

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyPharmacological CharacterizationBiochemistryMedicinePharmacological Agent +5

Proteoglycan degradation by a chondrocyte metalloprotease

C.B. Caputo, Donald J. Wolanin, Richard A. Roberts, +5

Biochemical Pharmacology

BiochemistryMedicineNatural SciencesMetalloproteinProteoglycan Degradation +5

Protease inhibitors decrease rabbit cartilage degradation after meniscectomy

C.B. Caputo, Linda A. Sygowski, Steven P. Patton, +4

Journal of Orthopaedic Research®

Protease InhibitorsRegenerative MedicineTissue EngineeringControl GroupMusculoskeletal Research +12