Donald W. Andisik

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Philip D. Edwards, Jeffrey S. Albert, Mark Sylvester et al. · Journal of Medicinal Chemistry · 2007 · 211 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthetic methods. 19. Lewis acid catalyzed conversion of alkenes and alcohols to azides

Richard Fibiger, Donald W. Andisik · The Journal of Organic Chemistry · 1984 · 74 citations

Natural Sciences, Chemistry, Biocatalysis +6

Peptidyl .alpha.-ketoheterocyclic inhibitors of human neutrophil elastase. 2. Effect of varying the heterocyclic ring on in vitro potency

Philip D. Edwards, Donald J. Wolanin, Donald W. Andisik et al. · Journal of Medicinal Chemistry · 1995 · 69 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Nonpeptidic Inhibitors of Human Leukocyte Elastase. 3. Design, Synthesis, X-ray Crystallographic Analysis, and Structure-Activity Relationships for a Series of Orally Active 3-Amino-6-phenyl-2-pyridinyl Trifluoromethyl Ketones

Peter R Bernstein, Donald W. Andisik, Prudence K. Bradley et al. · Journal of Medicinal Chemistry · 1994 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Discovery and Biological Activity of Orally Active Peptidyl Trifluoromethyl Ketone Inhibitors of Human Neutrophil Elastase

Philip D. Edwards, Donald W. Andisik, Craig A. Bryant et al. · Journal of Medicinal Chemistry · 1997 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13