Jeffrey S. Albert

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Philip D. Edwards, Jeffrey S. Albert, Mark Sylvester et al. · Journal of Medicinal Chemistry · 2007 · 211 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation

Stefan Geschwindner, Lise‐Lotte Olsson, Jeffrey S. Albert et al. · Journal of Medicinal Chemistry · 2007 · 148 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase

Miles Congreve, David Aharony, Jeffrey S. Albert et al. · Journal of Medicinal Chemistry · 2007 · 143 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Mechanistic studies of alkene epoxidation catalyzed by nickel(II) cyclam complexes. Oxygen-18 labeling and substituent effects

Joanne F. Kinneary, Jeffrey S. Albert, Cynthia J. Burrows · Journal of the American Chemical Society · 1988 · 122 citations

Natural Sciences, Chemistry, Catalysis +12

Stabilization of Helical Domains in Short Peptides Using Hydrophobic Interactions

Jeffrey S. Albert, Andrew D. Hamilton · Biochemistry · 1995 · 91 citations

Life Sciences, Biochemistry, Molecular Biology +15