Stefan Geschwindner

Structural insight into allosteric modulation of protease-activated receptor 2

R.K. Cheng, Cédric Fiez-Vandal, Oliver Schlenker et al. · Nature · 2017 · 246 citations

Signal Transduction, Biochemistry, G Protein-coupled Receptor +6

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Philip D. Edwards, Jeffrey S. Albert, Mark Sylvester et al. · Journal of Medicinal Chemistry · 2007 · 210 citations · Full text

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation

Stefan Geschwindner, Lise‐Lotte Olsson, Jeffrey S. Albert et al. · Journal of Medicinal Chemistry · 2007 · 148 citations · Full text

Medicinal Chemistry, Drug Target, Fragment-based Lead Generation +15

Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints

K. A. P. Edman, Ali Hosseini, Magnus Bjursell et al. · Structure · 2015 · 110 citations · Full text

Systems Biology, Signal Transduction, Developmental Biology +12

Crystal structure of microsomal prostaglandin E₂synthase provides insight into diversity in the MAPEG superfamily

Tove Sjögren, Johan Nord, Margareta Ek et al. · Proceedings of the National Academy of Sciences · 2013 · 98 citations · Full text