Heptares Therapeutics (United Kingdom)

Institution (Company)

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Heptares Therapeutics (United Kingdom)

339

Publications

77K

Citations

Authors

106

Concepts

About

Heptares Therapeutics (United Kingdom) is a company institution in Welwyn Garden City, United Kingdom known for medicine, biochemistry, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	28	210	38.7K
2	Natural Sciences	18	98	17.1K
3	Engineering	8	15	828
4	Health Sciences	1	1	81
5	Public Health	1	1	33

Heptares Therapeutics (United Kingdom)

339

Publications

77K

Citations

Page 1

	Year	Citations
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation Guillaume Lebon, Tony Warne, Patricia C. Edwards, Nature Molecular PharmacologySignal TransductionMolecular PhysiologyBiochemistryCommon Features	2011	871
Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine A.S. Dore, N.J. Robertson, James C. Errey, Structure Molecular PharmacologyMolecular PhysiologySignal TransductionBiochemistryG Protein-coupled Receptor	2011	546
Structure of class B GPCR corticotropin-releasing factor receptor 1 Kaspar Hollenstein, James Kean, Andrea Bortolato, Nature Signal TransductionMolecular PhysiologyG Protein-coupled ReceptorReceptor (Biochemistry)Molecular Biology	2013	408
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain A.S. Dore, Krzysztof Okrasa, Jayesh C. Patel, Nature Molecular PharmacologySignal TransductionMolecular PhysiologyBiochemistryG Protein-coupled Receptor	2014	407
Discovery of 1,2,4-Triazine Derivatives as Adenosine A<sub>2A</sub> Antagonists using Structure Based Drug Design Miles Congreve, Stephen P. Andrews, A.S. Dore, Journal of Medicinal Chemistry Combinatorial ChemistryCompound 4KPharmacotherapyPharmaceutical ChemistryMolecular Pharmacology	2012	301
Intracellular allosteric antagonism of the CCR9 receptor Christine Oswald, Mathieu Rappas, James Kean, Nature InflammationSignal TransductionG Protein-coupled ReceptorImmunologyReceptor (Biochemistry)	2016	270
Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein Javier García‐Nafría, Yang Lee, Xiao‐chen Bai, eLife	2018	267
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons Tobias Weinert, Natacha Olieric, R.K. Cheng, Nature Communications	2017	263
Structural insight into allosteric modulation of protease-activated receptor 2 R.K. Cheng, Cédric Fiez-Vandal, Oliver Schlenker, Nature Signal TransductionBiochemistryG Protein-coupled ReceptorNatural SciencesMedicine	2017	246
Extra-helical binding site of a glucagon receptor antagonist Ali Jazayeri, A.S. Dore, Daniel Lamb, Nature Molecular PharmacologyMolecular PhysiologyBiochemistryG Protein-coupled ReceptorMedicine	2016	224

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