Heptares Therapeutics (United Kingdom)

Statistics

Publications

364

Citations

87.1K

Authors

Location

Welwyn Garden City, United Kingdom

Heptares Therapeutics (United Kingdom) is a company institution in Welwyn Garden City, United Kingdom known for pharmacology, ligand binding, and drug discovery.

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Top concepts

PharmacologyLigand BindingDrug DiscoveryMedicinal ChemistryReceptor-ligand InteractionsMedicineReceptor PharmacologyStructural BiologyDrug DesignBiochemistry

Publications

364

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

Guillaume Lebon, Tony Warne, Patricia C. Edwards et al. · Nature · 2011 · 883 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

A.S. Dore, N.J. Robertson, James C. Errey et al. · Structure · 2011 · 553 citations · Full text

Medicine, Molecular Biology, Pharmacology +13

Structure of class B GPCR corticotropin-releasing factor receptor 1

Kaspar Hollenstein, James Kean, Andrea Bortolato et al. · Nature · 2013 · 414 citations

Life Sciences, Biochemistry, Molecular Biology +10

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

A.S. Dore, Krzysztof Okrasa, Jayesh C. Patel et al. · Nature · 2014 · 411 citations

Life Sciences, Molecular Biology, Neuroscience +12

Discovery of 1,2,4-Triazine Derivatives as Adenosine A<sub>2A</sub> Antagonists using Structure Based Drug Design

Miles Congreve, Stephen P. Andrews, A.S. Dore et al. · Journal of Medicinal Chemistry · 2012 · 304 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

1–5 of 364

Authors

FH
Fiona H. Marshall
Heptares Therapeutics (United Kingdom), United Kingdom
188 publications · 15K citations
60
h-index
MC
Miles Congreve
Heptares Therapeutics (United Kingdom), United Kingdom
224 publications · 24.4K citations
45
h-index
JC
James C. Errey
Heptares Therapeutics (United Kingdom), United Kingdom
80 publications · 5K citations
34
h-index
AD
A.S. Dore
Heptares Therapeutics (United Kingdom), United Kingdom
90 publications · 5.5K citations
31
h-index
MW
Malcolm Weir
Heptares Therapeutics (United Kingdom), United Kingdom
52 publications · 4.8K citations
29
h-index

1–5 of 38