Stephen P. Andrews

Discovery of 1,2,4-Triazine Derivatives as Adenosine A_2A Antagonists using Structure Based Drug Design

Miles Congreve, Stephen P. Andrews, A.S. Dore et al. · Journal of Medicinal Chemistry · 2012 · 301 citations · Full text

Combinatorial Chemistry, Compound 4K, Pharmacotherapy +16

Extra-helical binding site of a glucagon receptor antagonist

Ali Jazayeri, A.S. Dore, Daniel Lamb et al. · Nature · 2016 · 224 citations

Molecular Pharmacology, Molecular Physiology, Biochemistry +7

Crystal structure of the GLP-1 receptor bound to a peptide agonist

Ali Jazayeri, Mathieu Rappas, Alastair Brown et al. · Nature · 2017 · 193 citations

Glp-1 Receptor Bound, Crystal Structure, Biochemistry +7

Identification of Novel Adenosine A_2A Receptor Antagonists by Virtual Screening

Christopher J. Langmead, Stephen P. Andrews, Miles Congreve et al. · Journal of Medicinal Chemistry · 2012 · 133 citations · Full text

Enabled Homology Models, Drug Target, Pharmacotherapy +16

Enantioselective Preparation of 1,1‐Diarylethanes: Aldehydes as Removable Steering Groups for Asymmetric Synthesis

Thomas C. Fessard, Stephen P. Andrews, Hajime Motoyoshi et al. · Angewandte Chemie International Edition · 2007 · 123 citations

One-pot 1,4-Addition/decarbonylation Sequence, Convenient Procedures, Engineering +12