Alastair Brown - Concepedia

Author

Alastair Brown

Also Known As

A. J. H. Brown, A.J.H. Brown, Alastair Brown, Alastair J Brown, Alastair J H Brown, Alastair J. Brown, Alastair J. H. Brown, Alastair J.H. Brown, Alastair JH. Brown, Brown, Alastair J. H.

Publications

2.7K

Citations

H-Index

Concepts

All Affiliations

Heptares Therapeutics (United Kingdom)AstraZeneca (United Kingdom)University of Nottingham Monash University University of Cambridge

About

Alastair Brown is an author at Heptares Therapeutics (United Kingdom) specializing in medicine, pharmacology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	925
2	Health Sciences	5	5	469
3	Natural Sciences	1	1	193
4	Public Health	1	1	33
5	Social Sciences	1	1	30

Alastair Brown

Publications

1.5K

Citations

H-Index

Page 1

	Year	Citations
Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids Mohamed S. Zaïbi, Claire J. Stocker, Jacqueline O’Dowd, FEBS Letters Gpr41 Knockout MiceMurine Adipose TissueLeptin SecretionInsulin SignalingGastrointestinal Peptide Hormone	2010	330
Extra-helical binding site of a glucagon receptor antagonist Ali Jazayeri, A.S. Dore, Daniel Lamb, Nature Molecular PharmacologyMolecular PhysiologyBiochemistryG Protein-coupled ReceptorMedicine	2016	224
Crystal structure of the GLP-1 receptor bound to a peptide agonist Ali Jazayeri, Mathieu Rappas, Alastair Brown, Nature Glp-1 Receptor BoundCrystal StructureBiochemistryG Protein-coupled ReceptorNatural Sciences	2017	193
Differential Signaling by Splice Variants of the Human Free Fatty Acid Receptor GPR120 Sarah‐Jane Watson, Alastair Brown, Nicholas D. Holliday Molecular Pharmacology	2012	132
From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease Alastair Brown, Sophie J. Bradley, Fiona H. Marshall, Cell Molecular PharmacologyNeurodegenerative DiseasesAlzheimer's DiseaseMedicineMechanism Of Action	2021	87
Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor Karen Coopman, Russell Wallis, Graeme R. Robb, Molecular Endocrinology	2011	51
Drug Discovery Opportunities and Challenges at G Protein Coupled Receptors for Long Chain Free Fatty Acids Nicholas D. Holliday, Sarah‐Jane Watson, Alastair Brown Frontiers in Endocrinology Drug TargetInsulin SignalingGastrointestinal Peptide HormoneObesityMetabolic Syndrome	2012	51
Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias Joanne Hothersall, Rubben Torella, Sian Humphreys, Neuropharmacology	2017	47
Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits Jon Palacios-Filardo, Matt Udakis, Giles A. Brown, Nature Communications	2021	43
Use of a new proximity assay (NanoBRET) to investigate the ligand‐binding characteristics of three fluorescent ligands to the human<i>β</i><sub>1</sub>‐adrenoceptor expressed in HEK‐293 cells Mark Soave, Leigh A. Stoddart, Alastair Brown, Pharmacology Research & Perspectives	2016	37

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