Concepedia

Andrea Bortolato

AB

27

Publications

2.2K

Citations

20

H-Index

2007

Active since

Affiliations

Heptares Therapeutics (United Kingdom)(Current)

University of Padua

Bristol-Myers Squibb (United States)

Lundbeck (Denmark)

Schrodinger (United States)

Andrea Bortolato is an author at Heptares Therapeutics (United Kingdom) specializing in medicine, biochemistry, and drug discovery.

Top concepts

MedicineBiochemistryDrug DiscoveryMolecular DockingPharmacologyBiophysicsEngineeringNatural SciencesMolecular BiologyMolecular Modeling

Publications per year

2007–2024

27

Publications

27

Structure of class B GPCR corticotropin-releasing factor receptor 1

Kaspar Hollenstein, James Kean, Andrea Bortolato et al. · Nature · 2013 · 408 citations

Signal Transduction, Molecular Physiology, G Protein-coupled Receptor +3

Extra-helical binding site of a glucagon receptor antagonist

Ali Jazayeri, A.S. Dore, Daniel Lamb et al. · Nature · 2016 · 224 citations

Molecular Pharmacology, Molecular Physiology, Biochemistry +7

Crystal structure of the GLP-1 receptor bound to a peptide agonist

Ali Jazayeri, Mathieu Rappas, Alastair Brown et al. · Nature · 2017 · 193 citations

Glp-1 Receptor Bound, Crystal Structure, Biochemistry +7

Controlling the Dissociation of Ligands from the Adenosine A <sub>2A</sub> Receptor through Modulation of Salt Bridge Strength

Elena Segala, Dong Guo, R.K. Cheng et al. · Journal of Medicinal Chemistry · 2016 · 189 citations · Full text

Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors

Kyle D. Konze, Pieter H. Bos, Markus K. Dahlgren et al. · Journal of Chemical Information and Modeling · 2019 · 135 citations · Full text

Rows per page

1–5 of 27