Andrea Bortolato - Concepedia

Author

Andrea Bortolato

Heptares Therapeutics (United Kingdom)ORCID

Also Known As

A Bortolato, A. Bortolato, Andrea Bortolato, Bortolato, Andrea

Publications

3.6K

Citations

H-Index

Concepts

All Affiliations

Heptares Therapeutics (United Kingdom)University of Padua Bristol-Myers Squibb (United States)Lundbeck (Denmark)Schrodinger (United States)

About

Andrea Bortolato is an author at Heptares Therapeutics (United Kingdom) specializing in medicine, biochemistry, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	851
2	Biochemistry	8	8	631
3	Engineering	4	4	126
4	Natural Sciences	4	4	357
5	Biomolecular Engineering	1	1	39

Andrea Bortolato

Publications

2.2K

Citations

H-Index

Page 1

	Year	Citations
Structure of class B GPCR corticotropin-releasing factor receptor 1 Kaspar Hollenstein, James Kean, Andrea Bortolato, Nature Signal TransductionMolecular PhysiologyG Protein-coupled ReceptorReceptor (Biochemistry)Molecular Biology	2013	408
Extra-helical binding site of a glucagon receptor antagonist Ali Jazayeri, A.S. Dore, Daniel Lamb, Nature Molecular PharmacologyMolecular PhysiologyBiochemistryG Protein-coupled ReceptorMedicine	2016	224
Crystal structure of the GLP-1 receptor bound to a peptide agonist Ali Jazayeri, Mathieu Rappas, Alastair Brown, Nature Glp-1 Receptor BoundCrystal StructureBiochemistryG Protein-coupled ReceptorNatural Sciences	2017	193
Controlling the Dissociation of Ligands from the Adenosine A <sub>2A</sub> Receptor through Modulation of Salt Bridge Strength Elena Segala, Dong Guo, R.K. Cheng, Journal of Medicinal Chemistry	2016	189
Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors Kyle D. Konze, Pieter H. Bos, Markus K. Dahlgren, Journal of Chemical Information and Modeling	2019	135
Coumarin as Attractive Casein Kinase 2 (CK2) Inhibitor Scaffold: An Integrate Approach To Elucidate the Putative Binding Motif and Explain Structure–Activity Relationships Adriana Chilin, Roberto Battistutta, Andrea Bortolato, Journal of Medicinal Chemistry	2008	132
Water Network Perturbation in Ligand Binding: Adenosine A<sub>2A</sub>Antagonists as a Case Study Andrea Bortolato, B.G. Tehan, Michael S. Bodnarchuk, Journal of Chemical Information and Modeling	2013	117
The ATP‐Binding Site of Protein Kinase CK2 Holds a Positive Electrostatic Area and Conserved Water Molecules Roberto Battistutta, Marco Mazzorana, Laura Cendron, ChemBioChem	2007	98
Exploring Molecular Mechanisms of Ligand Recognition by Opioid Receptors with Metadynamics Davide Provasi, Andrea Bortolato, Marta Filizola Biochemistry	2009	87
High end GPCR design: crafted ligand design and druggability analysis using protein structure, lipophilic hotspots and explicit water networks Jonathan S. Mason, Andrea Bortolato, Dahlia R. Weiss, In Silico Pharmacology Chemical BiologyMedicinal ChemistryExplicit Water NetworksBiochemistryDrug Design	2013	86

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