Concepedia

Kyle D. Konze

KD

9

Publications

1.1K

Citations

9

H-Index

2013

Active since

Affiliations

Schrodinger (United States)(Current)

Structural Genomics Consortium

University of Toronto

University of North Carolina at Chapel Hill

Icahn School of Medicine at Mount Sinai

Kyle D. Konze is an author at Schrodinger (United States) specializing in medicine, drug discovery, and biochemistry.

Top concepts

Publications per year

2013–2020

9

Publications

9

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

Kyle D. Konze, Anqi Ma, Fengling Li et al. · ACS Chemical Biology · 2013 · 464 citations · Full text

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Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia

Bowen Xu, Doan M. On, Anqi Ma et al. · Blood · 2014 · 228 citations · Full text

Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors

Kyle D. Konze, Pieter H. Bos, Markus K. Dahlgren et al. · Journal of Chemical Information and Modeling · 2019 · 135 citations · Full text

Selective Inhibitors of Protein Methyltransferases

H. Ümit Kanıskan, Kyle D. Konze, Jian Jin · Journal of Medicinal Chemistry · 2014 · 127 citations · Full text

, , +17

Structure–Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors

Xiaobao Yang, Fengling Li, Kyle D. Konze et al. · Journal of Medicinal Chemistry · 2016 · 59 citations · Full text

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