Pieter H. Bos

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

Michael M. Gaschler, Alexander A. Andia, Hengrui Liu et al. · Nature Chemical Biology · 2018 · 717 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Multivalent Small-Molecule Pan-RAS Inhibitors

Matthew Welsch, Anna Kaplan, Jennifer M. Chambers et al. · Cell · 2017 · 283 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds

Alena Rudolph, Pieter H. Bos, Auke Meetsma et al. · Angewandte Chemie International Edition · 2011 · 156 citations · Full text

Natural Sciences, Chemistry, Biocatalysis +10

Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors

Kyle D. Konze, Pieter H. Bos, Markus K. Dahlgren et al. · Journal of Chemical Information and Modeling · 2019 · 143 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Catalytic asymmetric carbon–carbon bond formation via allylic alkylations with organolithium compounds

Manuel Pérez, Martín Fañanás‐Mastral, Pieter H. Bos et al. · Nature Chemistry · 2011 · 118 citations · Full text

Natural Sciences, Chemical Engineering, Chemistry +13