Concepedia

Elena Segala

ES

9

Publications

740

Citations

9

H-Index

2012

Active since

Affiliations

Heptares Therapeutics (United Kingdom)(Current)

University of Verona

Leiden University

Centre for Human Drug Research

Elena Segala is an author at Heptares Therapeutics (United Kingdom) specializing in medicine, molecular physiology, and viral pathogenesis.

ORCID

Top concepts

Publications per year

2012–2024

9

Publications

9

Structures of Human A 1 and A 2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity

R.K. Cheng, Elena Segala, N.J. Robertson et al. · Structure · 2017 · 216 citations · Full text

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Controlling the Dissociation of Ligands from the Adenosine A <sub>2A</sub> Receptor through Modulation of Salt Bridge Strength

Elena Segala, Dong Guo, R.K. Cheng et al. · Journal of Medicinal Chemistry · 2016 · 189 citations · Full text

New Mutations in the Mycobacterial ATP Synthase: New Insights into the Binding of the Diarylquinoline TMC207 to the ATP Synthase C-Ring Structure

Elena Segala, Wladimir Sougakoff, Aurélie Chauffour et al. · Antimicrobial Agents and Chemotherapy · 2012 · 119 citations · Full text

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals

Prakash Rucktooa, R.K. Cheng, Elena Segala et al. · Scientific Reports · 2018 · 92 citations · Full text

Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A<sub>2A</sub> Receptor

Tasia Amelia, Jacobus P. D. van Veldhoven, Matteo Falsini et al. · Journal of Medicinal Chemistry · 2021 · 40 citations · Full text

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