Malcolm Weir

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

A.S. Dore, N.J. Robertson, James C. Errey et al. · Structure · 2011 · 546 citations · Full text

Molecular Pharmacology, Molecular Physiology, Signal Transduction +9

Structure of class B GPCR corticotropin-releasing factor receptor 1

Kaspar Hollenstein, James Kean, Andrea Bortolato et al. · Nature · 2013 · 408 citations

Signal Transduction, Molecular Physiology, G Protein-coupled Receptor +3

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

A.S. Dore, Krzysztof Okrasa, Jayesh C. Patel et al. · Nature · 2014 · 407 citations

Molecular Pharmacology, Signal Transduction, Molecular Physiology +9

Discovery of 1,2,4-Triazine Derivatives as Adenosine A_2A Antagonists using Structure Based Drug Design

Miles Congreve, Stephen P. Andrews, A.S. Dore et al. · Journal of Medicinal Chemistry · 2012 · 301 citations · Full text

Combinatorial Chemistry, Compound 4K, Pharmacotherapy +16

Extra-helical binding site of a glucagon receptor antagonist

Ali Jazayeri, A.S. Dore, Daniel Lamb et al. · Nature · 2016 · 224 citations

Molecular Pharmacology, Molecular Physiology, Biochemistry +7