Lise‐Lotte Olsson

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Philip D. Edwards, Jeffrey S. Albert, Mark Sylvester et al. · Journal of Medicinal Chemistry · 2007 · 211 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Inhibition of Lipid Peroxidation by Spin Labels

Ulf Nilsson, Lise‐Lotte Olsson, Gunnar Carlin et al. · Journal of Biological Chemistry · 1989 · 177 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation

Stefan Geschwindner, Lise‐Lotte Olsson, Jeffrey S. Albert et al. · Journal of Medicinal Chemistry · 2007 · 148 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease

Fredrik Jeppsson, Susanna Eketjäll, Juliette Janson et al. · Journal of Biological Chemistry · 2012 · 138 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo

Claire Dobson, Paul W. A. Devine, Jonathan J. Phillips et al. · Scientific Reports · 2016 · 123 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17