Fredrik Jeppsson

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 529 citations

Medicine, Cancer Biology, Oncology +4

Characterization of AZD4694, a novel fluorinated Aβ plaque neuroimaging PET radioligand

Anders Juréus, Britt‐Marie Swahn, Johan Sandell et al. · Journal of Neurochemistry · 2010 · 140 citations

Medicine, Nuclear Medicine, Pharmacology +17

Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease

Fredrik Jeppsson, Susanna Eketjäll, Juliette Janson et al. · Journal of Biological Chemistry · 2012 · 138 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics

Susanna Eketjäll, Juliette Janson, Karin Kaspersson et al. · Journal of Alzheimer s Disease · 2016 · 131 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Brent D. G. Page, Nicholas C.K. Valerie, Roni H. G. Wright et al. · Nature Communications · 2018 · 124 citations · Full text

Medicine, Molecular Biology, Oncology +16